Why Great Content Still Falls Flat: The Global-to-Local Disconnect

There’s a silent gap in Medical Communications—and it’s not about effort, it’s about alignment. In this episode of Transforming Medical Communications, host Wesley Portegies is joined by Simon Priou, an experienced global content leader, to unpack the persistent challenges between Global, Regional, and Local teams.

There’s a silent gap in Medical Communications—and it’s not about effort, it’s about alignment.

In this episode of Transforming Medical Communications, host Wesley Portegies is joined by Simon Priou, an experienced global content leader, to unpack the persistent challenges between Global, Regional, and Local teams.

This conversation goes beyond content production—it reveals the human dynamics and workflow challenges that often prevent globally developed materials from being adapted, adopted, or impactful at the local level.

Whether you’re building affiliate toolkits or bridging silos, this episode offers a strategic lens on what actually enables trust, usability, and relevance across regions.

In this episode, you’ll learn how to:

Move from ‘content push’ to ‘collaborative pull’ by engaging regions and countries early
Localize with precision without compromising science or timelines
Identify the trust blockers that quietly erode alignment
Close the loop with feedback that drives measurable improvement

Before you hit play, ask yourself: Are you creating content that travels—or content that lands?

Previous guests include: Sissy Easo-Joseph at GSK, Barbara Bish at Janssen, Drew Provan at Queen Mary University, Rebecca McCracken at Agios Pharmaceuticals

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Transforming Medical Communications is handcrafted by our friends over at: fame.so

Disclaimer: The opinions and views expressed by the guest are their own and do not represent any past or current employers.